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Anti-inflammatory activity of compounds is achieved by modulating IL-1β secretion and prostaglandin E2 synthesis in macrophages and by inhibiting calcineurin phosphatase activity in lymphocytes.
Good separation of all these compounds is achieved at a column temperature of 30 °C (Fig. 1a).
The anti-inflammatory effect of these compounds is achieved because they directly block the pro-inflammatory and chemotactic functions of extracellular CyPA.
into solid tumour via the common iliac artery that is mainly feeding the tumour, so that effective delivery of these compounds is achieved.
A better performance for the heaviest compounds is achieved as well, since it avoids discrimination observed for these compounds during GC injection at high temperatures [ 15, 16].
In sphingomonads Sphingobium sp. SYK-6, Novosphingobium sp. strain PP1Y, N. aromaticivorans strain DSM12444, and another Novosphingobium strain with sequence-related homologues to Lig enzymes, strain B-7, it appears that metabolism of α-keto-β-ether-linked compounds is achieved via catalysis by multiple Lig β-etherases with overlapping function.
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The chromatographic separation of the compounds was achieved in a chromatographic run of 25.5 min.
The synthesis of these compounds was achieved in 36 69% overall yields from d-tartaric acid.
Characterization of the target compounds was achieved by NMR, IR, GPC and MALDI-TOF mass spectrometry.
In this proof-of-concept study, the synthesis of several previously unreported macrocyclic compounds was achieved.
Rapid and complete dechlorination of several chlorinated organic solvents and chlorinated aromatic compounds was achieved by using the nanoscale bimetallic particles.
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