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No significant difference was observed between the different compounds in terms of GRPR affinity.
Cerium oxide based materials are versatile compounds in terms of properties and applications.
The optimum hydrophobicity of compounds in terms of their log P values was calculated to be ≈4.1.
The next ring depicts the biological activity of the compounds in terms of MIC ≤ 50 μg/ml and mycobacterial growth % inhibition > 90.
While similar in structure, there are key differences between the available compounds in terms of dosing/dosimetry, pharmacokinetics, and interpretation of visual reads.
It can provide detailed inhibitory kinetic data for individual inhibitory compounds in terms of continuing cellular growth and final cell mass.
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The present study reports that J. dolomiaea, A. gracilis, and S. cordata are potential source of bioactive compounds in term of flavonoids, phlobatannins, phenolics, alkaloids, anthraquinones, saponins, coumarins, tannins, terpenoids, and cardiac glycosides.
"It was an unusual compound in terms of size and the privacy of it being isolated from anything connected to the world.
This approach may enable a comprehensive understanding of compound in terms of mechanism-of-action, associated pathways and phenotypic profile.
The Molecular Framework gives an overall description of the compound in terms of aliphaticity/aromaticity and number of cycles.
The amino-benzosuberone derivative 4 is the most promising compound in terms of potency, stability and selectivity.
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