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Over the past decade, evidence that vegetative volatile compounds function to directly repel herbivores has begun to accumulate [39], [46].
It is worth noting here that a small number of compounds function to elevate phosphoinositide levels, although we have not explored these compounds further in this paper.
Our data also suggest that these compounds function to deacidify the lysosome and thus, inhibit the delivery and degradation of autophagic vesicles, similar to CQ. Importantly, we demonstrate that autophagy inhibitors decrease cell viability, both as single agents and in combination, supporting the hypothesis that autophagy promotes melanoma cell survival.
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A working model of how this class of compounds functions to antagonize the AR was created.
These cells a very important due to their role in secreting signaling compounds that function to transmit information from one cell to another.
In all cases mentioned above, sex pheromones were characterised or presumed to be a blend of compounds functioning synergistically to attract males and elicit mating behaviour, and could contain both fertility-linked compounds as well as compounds which were produced mainly by virgin females.
There are several studies suggesting that organosulfur compounds function as an antimicrotubule agent similarly to Vinca alkaloids.
The biological significance of most ligands that activate mouse VNO neurons has not been elucidated [29], [30] therefore, it is striking that each of these approaches identified different compounds that similarly function to advance the onset of female puberty.
However, at present, the results of this study do not allow us to determine whether these compounds function as a radiation protectant, a radiation mitigator, or both.
Furthermore, a different response to C6-aldehydes was observed with three lepidopteron herbivores of Nicotiana attenuata where these compounds function as feeding stimulants for the larvae [21].
Our experiments demonstrated further that all these neuroprotective compounds function within the unfolded protein response during ER stress and they operate through different branches of this pathway to achieve neuroprotection (Vaccaro et al., 2013).
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