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This study was designed to characterize compounds from two thousands of insects of Blaps japanensis.
We used this assay to screen 1040 compounds from two commercial compound libraries, and identified 17 that promoted differentiation, as well as 5 that promoted survival of hESCs.
Herein, we prepare compounds from two classes of arylmorpholine PI3-K inhibitors and characterize their specificity against a comprehensive panel of targets within the PI3-K family.
We designed and tested compounds from two distinct chemicals series in a displacement assay of the two MT3 ligands, 2-[125I]-iodomelatonin 2-[125I]-iodomelatonin 2-[125I]-iodomelatoninetyltryptandne from their cloned target.
Lead compounds from two different chemical series, represented by compounds 17 and 38, displayed proficient in vitro reactivation of GF-inhibited hAChE, while also possessing low inhibition of native enzyme.
Moreover, the simultaneous emission of volatile compounds from two or more crops in the field hinders the location host plant.
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Recoveries of compounds from nine different matrices were quantitative.
Six compounds from three different chemical classes were used to optimize the extraction parameters.
In this study, a 3D-QSAR pharmacophore model was developed for potent and selective COX-1 inhibition based on 44 compounds from four different scaffolds using Phase, Schrödinger.
Using this animal model, the UCSF lab — and the affiliated institute, which had similar NIH funding earlier — has evaluated more than 100 chemical compounds from five dozen drug classes.
In this lesson, students study these scientists' discovery of cellular transportation systems – the compartments, called vesicles, that cells use to ferry compounds from one cell to another, or to carry materials within the cell — then build models of cells, showing how these vesicles work.
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