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Comparison of specificity, potency and mechanisms of action for each member would facilitate the selection of lead anti-Fli-1 compounds for potential use as single drugs or, if appropriate, combined formulations with potentially enhanced efficacy.
Screening chemical compounds for potential pharmacological effects is a very important process for drug discovery and development.
Pharmacopeia, which makes software for drug makers and develops compounds for potential medicines, said yesterday that it planned to spin off its drug-discovery business, change its name and move to San Diego.
We identified novel analogues with interesting properties that make them attractive lead compounds for potential topical applications.
Overall, these DPAH derivatives are exciting new compounds for potential application in actinide and lanthanide separations technologies.
In addition to being useful for drug development, this test could also be helpful for environmental regulatory agencies responsible for testing chemical compounds for potential harmful effects, Engelward says.
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According to our data, 7c may act as a lead compound for potential anticancer drugs.
We have recently defined the synthesis of novel diether PG analogs (two phosphoglycerols and one phosphonoglycerol compound) for potential combination with DEPN-8 or SO2-lipid in synthetic exogenous lung surfactants [52].
Mr. Carr's company, Amersham, produces sophisticated equipment used to help drug-company chemists screen millions of compounds for a potential reaction that could halt disease.
The results indicated some of the target molecules might be not a target-specific agent, may behave as a new lead compounds for highly potential cytotoxic agents.
So a stable mouse model can help to identify and evaluate specific compounds for their potential efficacy.
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