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Furthermore, significantly (p = 0.019) more patients who had stayed for at least two years in the compounds (27.4%) stated that TB could be transmitted through sharing of cups compared to 11.9% of patients who had stayed in the compounds for less than two years.
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Using only knowledge from the HR2 chemical formula generator, unique mass defines chemical space location only for compounds less than approximately 500 Da (Fig 4A), and only for 5% of all compounds.
For compounds containing less than 10 wt% ZnSt, the components were miscible.
For compounds with less than 100% agreement, neither method was consistently more sensitive than the other.
For compounds with less than 100% agreement, neither method was consistently more sensitive than the other in detecting the presence of a compound.
Chemical derivatization can dramatically increase the sensitivity and specificity of LC-MS for less polar compounds [42].
Our analysis shows that effects of the test system on response time are significant, particularly at lower concentrations and for less volatile compounds.
However, we suspect efficiencies are lower for less lipophilic compounds.
However, for less hydrophobic compounds such as TCEP and TCIPP, ∼ 20% of the total mass was partitioned into the intestinal fluid, which was slightly higher than the measured value in the sorption efficiency experiment using the spiking method (SI Figure S4).
The aim of this study is to develop and validate a multi-compound LC TOFMS method for compounds that are less suitable for GC MS methods.
However, for less well synchronized compounds, the addition of synaptic noise resulted in a significant increase in sigmaf, i.e. making the neuron more likely to respond even to poorly synchronized input events.
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