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Altogether, we concluded that SA1 and SA2 might be potential antidiabetic lead compounds for future drug development.
Two compounds were highly potent against the HL60 cell line and represent promising lead compounds for future development.
In 6 Hz screening these two compounds showed significant protection and emerged as lead compounds for future investigations.
A greater understanding of such interactions at the molecular level would contribute to the design of Pt compounds for future clinical use.
BENZOMATE and related analogues therefore represent an important class of non-steroidal STS inhibitor and lead compounds for future drug design.
Because of their ability to discriminate among channel isoforms, and their high degree of structural conservation, these toxins could serve as important lead compounds for future pharmaceutical design.
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LZO and PEDOT PSS CNT performance was enhanced to up 20%, indicating the most interesting compound for future use.
Results from this study provided a potential lead compound for future CCR5 antagonist development focusing on prostate cancer therapy.
This strong activity rivals currently used commercial fungicides, such as Boscalid and Carbendazim, and has great potential as a lead compound for future development of novel fungicides.
Compound 11 therefore represents a suitable lead compound for future drug development projects, due to its novel conformationally constrained structure, its "lead-like" properties and desirable affinity, efficacy and selectivity characteristics.
Such investigation might also provide a pool of chemical compounds critical for future biological target studies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com