Sentence examples for compounds for development from inspiring English sources

The identification of active components in natural products provides lead compounds for development into a drug.

This level of activity warrants further investigation of the compounds for development as anticancer and antimalarial agents.

Our data suggest that the 2,3-dihydrobenzofuran derivatives might be suitable bioinspired lead compounds for development of new generation mPGES-1 inhibitors with increased affinity.

Results from this study render NFAP2 of antifungal highly interesting compounds for development of a new antifungal strategy against yeasts after further studies focusing on its bulk production, antifungal mechanism, toxicity and in vivo activity.

These studies demonstrate that CADD can be used to identify lead compounds for development of novel non-ATP-dependent inhibitors selective for active ERK and its interactions with substrates involved in cancer cell proliferation.

At 50 mg/kg/day, 2b administered subcutaneously was lethal to infected mice (MST = 3 days) and moderately active when administered orally (IVI = 45 55%, MST = 25 days). 1 and 3 are promising compounds for development of antimalarials.

The results indicated that compound 8b is an excellent multifunctional promising compound for development of novel drugs for Alzheimer's disease (AD).

Our study suggested that single agents inhibiting Topo and PARP concurrently might be an alternative for cancer therapy and 11l represented a potential lead compound for development of antitumor agents.

TLM is also orally available and non-toxic in the mouse model, which makes it an attractive compound for development.

LK-A is therefore a potential lead compound for development of antitumor drugs targeting HCC.

IGR seems to be a suitable natural compound for development of new anti-inflammatory ingredient.