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With the live cell imaging systems, cellular activity like mode of death, proliferation and inhibition as a result nanoparticle or other compounds exposure can be studied.
This study was designed to determine cytotoxic effects of PBDE-47 and HBCDs individually or with a mixture of both compounds exposure to Hep G2 cells.
For these compounds, exposure via inhalation may be low for some individuals compared to these other routes of exposure.
CaBP-9k is a cytosolic calcium-binding protein expressed in various tissues (e.g., intestine, uterus, and placenta) and a marker of estrogenic compounds exposure (Choi et al. 2005).
CaBP-9k is a cytosolic calcium-binding protein expressed in various tissues (eg, intestine, uterus, and placenta) and a marker of estrogenic compounds exposure.
Effective reduction of exposures to HAPs requires determining the compounds, exposure pathways, and sources that contribute the most to human health risk.
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Classically, morphological assessment of the embryos is applied to evaluate the effects of compound exposure.
There was no direct correlation between compound exposure and in vivo activity.
After compound exposure, cell viability was assessed by the commonly used MTT assay.
Computational toxicology aims at predicting in silico the health and environmental risks associated to compound exposure or intake.
To determine if reducing DCU particle size would improve compound exposure, a 30 mg/kg oral suspension and two oral nanosuspension doses (10 and 30 mg/kg) were administered to SD rats.
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