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No one was depicting the compounds developed by Phenomenome Discoveries, synthetic plasmalogen precursors, as a cure for RCDP.
In the first phase of clinical trials, one of the compounds developed by the company reduced the level of the enzyme, known as Lp-PLA2, in patients.
They are also using libraries of compounds, developed by Stuart Schreiber at the Broad Institute, known to prevent the type of DNA alterations seen in leukemia.
There, a dozen chemists, biologists, and computer scientists test compounds developed by Yale and University of Connecticut researchers, for their potential as therapies.
Up to that, the 1,4-diazabicyclo[3.2.2]nonane derivatives [11C]NS14492 [18F]NS10743S10743 [21] and [18F]NS14490 [22], all based on compounds developed by NeuroSearch A/S (Ballerup, Denmark) [23],[24], were the most qualified promising radiotracers for imaging of α7 nAChR by PET.
Both isoforms are activated by the same oxysterol metabolites, and by nonsterol compounds developed by the pharmaceutical industry (for example GW 3965 or TO-901317).
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The deal clears the way for Intermagnetics to try to develop superconducting products for the utility industry using yttrium barium copper oxide, a ceramic compound developed by Lucent.
Mr. Mubarak's villa is in a compound developed by Hussein Salem, an Egyptian businessman and close friend of the former president.
The dual ETA ETB receptor antagonist bosentan, a nonpeptide sulfonamide compound developed by high-throughput screening13,14,15, is the first oral drug approved for the treatment of for PAH9,10,13,14.
One compound developed by Acucela that is in clinical trials inhibits the enzyme that converts the photopigment in photoreceptors from one form to another.
The most prominent case at Princeton is Alimta, an Eli Lilly cancer drug based on a compound developed by emeritus chemistry professor Edward C. Taylor.
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