Sentence examples for compounds capable of targeting from inspiring English sources
Antiviral research on HSV preliminarily focuses on compounds capable of targeting the viral polymerase.
In cellular studies, while a small number of luminescent RuII polypyridyl compounds capable of targeting nuclear DNA have been reported, studies into the cellular internalization of lipophilic luminescent RuII systems have frequently revealed non-nuclear localizations.
N. fruticans and O. stamineus extracts enabled the host to survive both antibiotic-sensitive and antibiotic-resistant S. aureus infection without interfering with bacterial viability, suggesting that these extracts possess compounds capable of targeting the host defense mechanism or attenuating bacterial virulence traits.
The active ingredient SkQ1 in Visomitin (Mitotech LLC, Moscow, Russian Federation) ophthalmic solution belongs to this class of compounds and is capable of targeting and neutralizing mitochondrial ROS [ 13, 14].
Collectively, these data support the hypothesis that C333 plays a critical role in determining the inhibitor sensitivity of Shp2, even in the presence of competing molecules that reduce the apparent potency of a compound that is capable of targeting the putative 333/367 allosteric site.
Recent research and developments have created the possibility of using NO donor compounds and designing new complex NO compounds capable of delivering NO directly into target tissues or to the bloodstream more efficaciously in a controlled or pulsatile manner.
This is with a view to develop reliable tools for screening new natural compounds capable of binding (and inactivating) bacterial target(s).
We herein describe the design, synthesis, molecular modeling and biological evaluation of a new series of donepezil-related compounds possessing metal chelating properties, and being capable of targeting different enzymatic systems related to AD (cholinesterases, ChEs, and monoamine oxidase A, MAO-A).
In summary, our mechanistic drug-screening strategy aimed at targeting EWS/Fli-1 has led to the identification of 30 compounds capable of inhibiting the function of this fusion oncoprotein.
172 High-throughput screening (HTS) methods have been used to discover small compounds capable of inhibiting PPI, especially when no structural information is available about the target proteins.
We also found RDP58 to be effective in reducing the compounding inflammatory damage brought on by chronic TPA exposure, and that it is capable of targeting inflammatory mediators specifically in the keratinocyte.
