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Compounds capable of stimulating soluble guanylate cyclase (sGC) activity might become important new tools to treat hypertension.
Small, orally active compounds capable of stimulating endogenous EPO production are in preclinical or clinical trials for treatment of anemia.
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I nducer: Diffusible chemical substances of a wide variety, including inorganic ions, chemical compounds, vitamins, and hormones capable of stimulating cell differentiation in the early stages of embryonic development, are commonly referred to as primary embryonic inducers.
Collectively, the data indicate that E. purpurea, at least, and possibly other plant compounds, appear to contain phytochemicals capable of stimulating de novo production of NK cells, as well as augmenting their cytolytic function, in animals of advanced age.
In addition, it was also observed that other phenolic compounds found in red wine were capable of stimulating autophagy [ 31].
This compound is biologically active and is capable of stimulating cell growth of an ER-positive cell line at low concentrations.
NAC is an excellent source of sulfhydryl compound, which converted in hepatocytes into metabolites capable of stimulating GSH synthesis; it also provides sufficient cysteine to promote detoxification and eliminates directly reactive oxygen species.
A number of microbial compounds capable of suppressing the immune response have been discovered.
Furthermore, the development of models capable of distinguishing compounds capable of activating T-cells need to be developed.
We recently identified niclosamide, perhexiline, and rottlerin as compounds capable of rapidly inducing autophagy [43].
They identified two novel compounds capable of lowering blood glucose, but these compounds also paradoxically activated pck1 expression.
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