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Ethyl acetate extracts contained compounds capable of retarding fungal growth of both T. versicolor and G. trabeum (Table 4); however the inability of the solvent to swell the cell wall due to its low polarity only partially removes the active compounds.
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A number of microbial compounds capable of suppressing the immune response have been discovered.
Furthermore, the development of models capable of distinguishing compounds capable of activating T-cells need to be developed.
We recently identified niclosamide, perhexiline, and rottlerin as compounds capable of rapidly inducing autophagy [43].
They identified two novel compounds capable of lowering blood glucose, but these compounds also paradoxically activated pck1 expression.
Four hit compounds capable of inhibiting >50% of the radioligand binding were examined further.
This led to clinical studies with several compounds capable of inhibiting NO synthesis.
Antiviral research on HSV preliminarily focuses on compounds capable of targeting the viral polymerase.
Similarly, volatiles from two stabilized elastomers were also capable of retarding a degradation process remotely.
We propose that these materials function by retarding cytokine diffusion, with the non-crosslinked polymers being capable of retarding the diffusion of cytokines in the extracellular matrix and preventing engagement with receptors.
CV PC, XN and GT hydrogels with release ratios of 37.15%, 32.79% and 29.39%, respectively, were capable of retarding release with respect to sole WPI hydrogels (p < 0.05).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com