Sentence examples for compounds bound with from inspiring English sources

A similar analysis was performed on another kinase panel by Davis et al.[35] where selectivity scores were computed for each kinase by dividing the number of compounds bound with Kd < 3 μM by the total number of compounds screened.

The detailed analysis of the wall constituents revealed significant differences in the content of phenolic compounds bound with the pectin and hemicellulose fractions.

Among the ligands from the NCI Diversity library no compounds bound with the S4 pocket have been identified, but all of them have P1 positively charged moiety that provides binding interactions with the negatively charged aspartate in the S1 pocket.

The G score of the compounds ranged between −2.9 and −0.4; 2-[ 3-methylbutoxy) carbonyl] benzoic acid had the highest G score in the isolated compounds, bound with HID 2-[ 3-methylbutoxy543: (H) HZ1, and LYS 543: (H) HZ1 residues of the COX-2-[ 3-methylbutoxy

The most often seen interaction is to Asp235, and most compounds bind with a specific orientation that is defined by their ability to interact with this residue.

As suggested by computational studies, all compounds bind with H+/K+ ATPase having good binding affinities.

Organophosphorus and carbamate compounds bind with variable affinity to the esteratic site by phosphorylation or decarbamylation, respectively, and inactivate the enzyme.

These three compounds bind with different affinities to B-cell lymphoma 2 (Bcl-2), BCL2L1 long isoform (Bcl-xL) and BCL2L2 (Bcl-w) proteins and displace Bak, Bad and Bax.

34 Both compounds bind with high affinity to the macrophilin-12 receptor and inhibit calcineurin, a calcium-dependent phosphatase that is required for activation of the nuclear factor of activated T cells (NF-AT).

Significant enhancement of fluorescent quantum yield was observed when the compound bound with HRAS G-quadruplex.

This compound binds with extraordinary affinity to all mammalian GSTs, with a KD of about 10−9 M and causing a complete enzyme inhibition.