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Nearly a dozen other compounds are under development.
Human trials for Folkman's anti-angiogenic compounds are under way at academic medical centers across the United States.
However, several studies show that the biosynthesis and accumulation of phenolic compounds are under dependence of hormonal factors: generally the plant growth stimulator (auxins, cytokinins, …) have a negative effect on these processes whereas growth inhibitors promote.
PP-like compounds are under development as potential anti-obesity agents, in light of the fact that short-term peripheral PP administration to lean people [16], [17] or to obese people with Prader Willi Syndrome [18], [19], [20] significantly reduces appetite and food intake.
Several novel compounds are under investigation.
Also in this case, new compounds are under development.
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In fact, almost all of the compounds are under-predicted at the median with the exception of DEHA, DEHP, and chlorpyrifos.
Possibly, the production of most of these compounds is under multigenic control and the corresponding regions cannot be detected with such a small population of segregants.
Presumably, the synthesis of many of these compounds is under multigenic control, such that the small size of our segregant population prevented exploration of their complexity.
Due to its low membrane permeability, esterified 5-aminolevulinic acid derivatives less hydrophilic than the parental compound are under investigation.
The mosque compound is under the day-to-day control of the Islamic Waqf, a religious authority, while Israel claims sovereignty.
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