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Most of the compounds are still shared by two or three families.
Known as beguinages or begijnhofs, several dozen of these compounds are still intact (to varying degrees) from England to Germany.
Arsenic compounds are still liberally used, both as insecticides and as weed killers, where they usually take the chemical form of sodium arsenite.
Hypocretin receptor agonists are likely to be ideal therapeutic options for hypocretin-deficient narcolepsy but such compounds are still not available in humans.
But the plant and its compounds are still illegal under US federal law, consigned to the most restricted category of substances — schedule 1.
Whilst early progress has been made in identifying LXRβ selective ligands, these initial compounds are still some way short of the desired functional selectivity profile.
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Though biological technologies offer a cheaper and more environmental friendly alternative for the treatment of textile effluents, an additional step to remove recalcitrant compounds is still needed.
Because the rationale of the therapy with platelet-derived compounds is still debated, a definitive insight can be acquired only when these large randomized trials will be completed.
The potential of vibrational optical activity (VOA) for chiral coordination compounds is still poorly explored, especially when compared with VOA's role in organic chemistry and biochemistry.
Analysis of phase transformation processes observed in most hydrogen-absorbing materials (pure metals, alloys or compounds) is still a matter of active research, in view of electrochemical or chemical hydrogen storage applications.
However, a problem of effective scoring and discrimination between active and inactive compounds is still not completely solved [1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com