Sentence examples for compounds are modified from inspiring English sources

It is especially significant that the three effective compounds are modified at the site of the acceptor atom in the natural substrate.

In phase I toxic compounds are modified resulting in more reactive metabolites.

Likewise, 1-methyladenosine and pseudouridine are markers of nucleic acid turnover; both these compounds are modified post-transcriptionally, and thus represent macromolecular degradation.

Many important natural compounds are modified cyclic peptides, for example, antibiotics like vancomycin (Fig.  1a), the immunosuppressant drug cyclosporin (Fig.  1b) and fungal toxins phalloidin or actinomycin D (Katsara et al. 2006).

Lead compounds were modified to investigate the possible role that zinc binding may play in inhibitor efficacy.

However, six different analogues of epothilones are in preclinical and clinical trials including patupilone (epothilone A and B), ixabepilone (BMS247550), BMS 310705, sagopilone (ZK-EPO), KOS-862 (epothilone D), and KOS-1584, etc. where all of these compounds were modified from major product of myxo-bacterium (epothilone A and B) (Cheng et al. [2008]).

We also wished to explore whether the impact of these compounds is modified by active tobacco smoke exposure.

A sensitivity analysis study is similar to genetic or chemical modification experiments in which specific features of a lead compound are modified to examine whether they affect properties such as binding affinity.

When an effect is detected, the compound is modified in different ways to optimize its activity and specificity.

The natural enantiopure compound is modified to create the desired enantiopure drug.

For each compound in the entire Vss-target dataset (including both the training (model selection) and external datasets), the value of the predicted adipose tissue's log Kt:p descriptor in that compound was modified by adding or subtracting 10% of the current descriptor value, where the decision to perform addition or subtraction was made at random.