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The title compounds are assembled from six sugar amino acid dipeptide isosteres and are synthesized using solution-phase peptide synthesis protocols.
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Library compounds were assembled at the Small Molecule Discovery Center from commercial sources.
These compounds were assembled with a modular build/couple/pair synthetic strategy using different olefin-containing carboxylic acid and amino alcohol building blocks.
A focused screening library of ~2000 compounds was assembled from an in-house collection of previously synthesized kinase inhibitors utilizing a single concentration screening approach in a Nek2 biochemical kinase assay.
A library of metabolites and structurally related compounds was assembled as described in the "Approach to the prediction of metabolic function associated with a TR" section and used to investigate the effector binding specificity of GST-B3018.
Compound pipes are assembled as a sequence of segments, each of which has a constant curvature.
Once the compound spectra are assembled, we use each as a query spectrum to various search methods.
In [25], the authors propose compound features that are assembled from simple 2D corners in both space and time.
Compounds 1 and 2, which are assembled through noncovalent interactions, were obtained by controlling the temperature.
Compounds 3 5 show 1D chain structures, which are assembled into 2D or 3D supramolecular frameworks via weak interactions.
128 target-based data sets are assembled that consist of at least 100 compounds with precisely specified equilibrium constants (K i values) below 1 µM for human targets.
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