Exact(60)
Amino acids, a very important class of compounds, are able to function both as acids and as bases.
This is the explanation for the fact that only a relatively small number of compounds are able to exhibit efficient luminescence.
The results indicated that the compounds are able to interact with Hsp90 ATP binding pocket and inhibit ATPase function.
These compounds are able to compete with natural substrates, such as specific transcription factors, and alter gene expression.
Pharmacophore modeling study revealed that these compounds are able to effectively satisfy the proposed common feature sites using energy accessible conformers (Econf < 20 kcal/mol).
We show that these compounds are able to enhance the permeability of a hydrophilic macromolecule, by opening the TJ for a shorter time than capsaicin.
Complexation studies using biologically important metal ions demonstrated that these compounds are able to bind Cu2+, Fe3+, Co2+, Ni2+ and Zn2+.
In addition, studies using in vitro HCV infection and replication models have shown that both compounds are able to significantly reduce viral genomic replication.
In addition, neuroprotective studies revealed that all these tested compounds are able to inhibit the neurotoxicity induced by Aβ and Fe/AscH in neuronal cells.
The investigations on the catalytic potential in the bulk polymerisation of lactide have shown that these compounds are able to act as initiators for lactide polymerisation with only few exceptions.
It is reported in the literature that some copper (II) coordination compounds are able to form double anti parallel polymer chains which are kept together by strong phosphate-water bonds [14, 20].
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