Sentence examples for compounds activity from inspiring English sources

As ChEMBL (unlike MDDR) contains numerical values of particular parameter determining compounds activity, active compounds were selected manually by setting an appropriate threshold – only compounds which annotated activity satisfied one of the conditions: Ki < 100 nM or IC50 < 200 nM, were included into active class.

Determination of interaction factor (IF), like isobolographic analysis, is independent on mechanism of active compounds activity and requires linear relationship between an activity and sample concentration.

The compounds activity was compared with the control (C = cells with activator).

In this study, we developed a scoring function for the identification of the active compounds in the AuPosSOM clustered dataset without prior knowledge of the compounds' activity.

In addition, SAR of the compounds activity was investigated and confirmed that the terminal aryl moiety was found to be quite crucial for DNA-PK activity.

The N-propargyl group as a substituent at position 1 of the 1,4-DHP cycle did not essentially influence the compounds' activity.

Let A denote a binary outcome termed compound activity where A = 1 for active and A = 0 for inactive.

Table 1 Comparative study for compound activity in an ARE-Luciferase reporter assay for AR-driven transcription and compound activity in CETSA HT.

Over time, chemical genomic approaches helped to increase the understanding of antibiotic activity but still lacked the ability to differentiate compound activity.

Compound activity patterns for all possible combinations of protein-protein interactions between VDR and its coregulator, coactivator, and corepressor and how individual compounds (agonists and antagonists) affect this interaction.

Thus, the presence of substructure (S_1) is significantly associated to compound activity.