Sentence examples for compounding these limitations from inspiring English sources

Compounding these limitations, L-DOPA therapy tends to lose effectiveness over time, L-DOPA-induced dyskinesias are a common complication of chronic dopaminergic therapy, and metabolites of this compound are neurotoxic [1].

The pharmacological inhibitors used to block autophagy by blocking class III PI3-Kinase further compound these limitations with their off-target effects.

An ongoing weakness was the lack of systems that ask and record Indigenous status in the data systems of Cancer Councils, compounding the limitations in this regard of other data systems providing information used by the Councils [ 22].

Compounding this limitation was our decision to limit the study sample to patients with at least 6 months of eligibility for medical and drug benefits before and after the "qualifying" hospitalization, and to exclude patients with evidence of both schizophrenia and bipolar mania.

Contention in the various SMP architectures tested is shown to compound these two hardware limitations.

In contrast to this, current risk assessment models used in the context of GYO not only lack this holistic approach but may compound this limitation by using highly precautionary assumptions that often result in unnecessary contaminant 'scares' being instigated, and do not provide predictions of health outcomes that can easily be communicated to the general public.

And politics tends to compound these problems.

The Depression compounded these pressures.

Compounding limitations of routine primary health care are weaknesses in the referral, triage, logistics, and care systems that prevent the implementation of adequate emergency health services [ 5].

In addition, smell disturbances associated with these conditions may further compound social limitations.

These limitations of modern genomics are compounded by limitations of conventional phenotyping.