Sentence examples for compound which causes from inspiring English sources

To test whether cisplatin, a synthetic platinum-containing compound which causes DNA crosslinking, is also capable of synergistically activating the expression of inflammatory genes and processing of IL-1β, we treated BMDM with cisplatin and vincristine, singly and in combination.

The most versatile agent of triazolo-pyrimidine-sulfonamides tested was compound which caused complete suppression of visible growth of S. cerevisiae, C. albicans, A. fumigatus, R. oryzae, and C. neoformans at the range of 1 8 μg mL−1.

Of the remaining fragments, by far the largest CSPs in MTIP were caused by hit 8, a compound which caused not only a positive Δ Tm by DSF (+5.6 °C), but also a notable sharpening of the melting transition, and hit 3. The interaction of 8 was further confirmed by running an NMR titration experiment, enabling measurement of its binding affinity.

We train our predictive models on the lowest formation enthalpy at each composition becauses they represent the most stable compounds, which causes our model to predict the energy of the ground-state structure given composition.

The degradation processes of the various Pb pigments yield a range of compounds which cause discolouration, strongly affecting the readability of the polychromy [200].

Grapevine tissues, like those in many higher plant species, contain abundant polyphenolic and polysaccharide compounds which cause challenges when isolating RNA.

The IC50 value is the concentration of test compounds which cause 50% inhibition or cell death, average from three experiments, and was obtained by plotting the percentage of inhibition versus the concentration of test compounds [ 13].

However, when present in high concentrations, FAs exert toxic effects by perturbing the cellular acid/base balance, disrupting membrane structures, and generating harmful ("lipotoxic") compounds, which cause cell and tissue dysfunction.

However, our previous work only characterized surfactant-based compounds, which cause epithelial damage, and we do not know whether soluble forms of selectins, which most likely arise by shedding or cleavage from the cell membrane, are suitable markers for other compounds that are toxic through other mechanisms.

Examples of these therapies are bifunctional alkylating agents and platinum compounds, which cause DNA crosslinks leading to DSBs during DNA replication, and poly(ADP-ribose polymerase (PADP-ribose polymerase8], which inhibit rePARP -inhibitorstrand DNA breaks also resulting in DSBs during rePARP -inhibitors

It's around three times stronger than normal cannabis thanks to higher levels of the compound THC, which causes the psychotic symptoms, and lower levels of another compound called cannabidiol, which experts think protects users from the effects of THC.