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The azaphilone compound was reported with a low molecular weight for lacking the acyl moiety on the side chain.
The first new tripodal compound was reported in 2000 by Berrocal et al. with sulfate recognition properties for anion-selective electrodes [1].
If the compound was reported to be active against more than one target, the highest measured bioactivity (for the compound) was retained.
Originally studied as an antibacterial molecule (Cornforth and James, 1956; Lightbown and Jackson, 1956), this is the first instance that a 4-quinolone compound was reported as a signalling molecule in bacteria.
The initial lead compound was reported by us previously, we continued to carry out structure activity relationship studies and optimize the lead structure to potent inhibitors in this research.
While damage to the compound was reported to be minor, affecting only one satellite dish, it could signal determination on the part of attackers to take aim at vulnerable civilian infrastructure.
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This compound is reported via a procedure based on an asymmetric aldol/ring closure metathesis strategy.
The syntheses, SAR studies, and evaluation of 3 as a lead compound are reported.
Synthesis, in vitro and in vivo evaluation of the most potent compound are reported.
In these curves, the score obtained for each compound is reported versus its rank given by the same program.
The potency of LHRH compound were reported to be as high as 5,00 10,00 folds compared to parent molecules.
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