Sentence examples for compound was rapidly from inspiring English sources
Plasma concentrations of ketoprofen remained detectable until 2 hours after administration, after which the compound was rapidly eliminated.
After intravenous administration of 2-MeOE2, the compound was rapidly cleared from the plasma, suggesting metabolic removal.
Although its behavior was as expected in rats (well absorbed, distribution to adipose and liver, long half-life, elimination in feces, limited metabolism), the parent compound was rapidly eliminated in the urine of mice.
It is therefore probable that the compound was rapidly metabolised by hepatic phase I metabolic processes in these experiments so that it was unable to exert pharmacodynamic effects on the animals.
If a test compound is rapidly metabolized, its in vivo bioavailability will probably be low [10].
To rescue the pinewoods with pine wilt diseases, it is important that the injected anti-nematodal compound be rapidly and widely dispersed once applied.
Therefore Pt(IV) would be expected to display higher flux rates across MCL than Pt II); unless the compound is rapidly converted into the parental Pt II) version.
Pharmacokinetic studies in mice have confirmed that the compound is rapidly eliminated from the plasma and that there is a prolonged terminal elimination phase.
Studies of DEHP disposition and metabolism in the African Green monkey and man show that the compound is rapidly and extensively metabolized.
When aflibercept is administered intravitreally, the compound is rapidly distributed to the retina and slowly absorbed by the systemic circulation, with an average free drug maximum plasma concentration (Cmax) of 0.02 µg/mL (interval 0 0.054 µg/mL) after a 2-mg intravitreal injection, in a period of 1 3 days, with concentrations becoming undetectable approximately 2 weeks after administration.
For example, for chemicals with short biological half-lives, such as bisphenol A (BPA), urine concentrations from one person can vary over the course of a single day because exposure occurs at meals and the compound is rapidly metabolized and excreted (Teeguarden et al. 2011).
