Sentence examples for compound to compete from inspiring English sources

We next tested whether 6AP and GA share the same interaction site(s) on ribosomal constituents by determining the ability of each compound to compete for the binding of ribosomal proteins to the other compound.

Interspecies interactions of oral streptococci involve the production and excretion of antimicrobial compounds to compete successfully during colonization.

In order to test this hypothesis, we assessed the ability of these test compounds to compete for binding of the radiolabeled MPEP analogue [H]3-methoxy-5- pyridin-2-ylethynyl pyridine) ([H]3-methoxy-5- pyridin-2-ylethynyl pyridineraction witH]3-methoxy-5- pyridin-2-ylethynyl pyridine

At that time, the biphasic effect of some quinones (inhibitory at low concentration and inactive or even activating at high concentration) was explained by hypothesizing (i) that quinones formed aggregates at high concentrations and (ii) that these aggregates were either inactive or activating compounds able to compete with the monomeric-inhibiting quinone.

Chemical compounds, able to compete with Brn3 transcription factors, may provide the basis for Brn3a-specific inhibitors (Peixoto et al, 2008).

Inactivation of Shiga toxins by antitoxin antibodies [ 185] and by certain synthetic carbohydrate and peptide compounds designed to compete with the active site of the toxin for receptor sites on cell membranes has also been investigated [ 186– 186].

Furthermore, the catechol compound was demonstrated to compete with pTyr peptides in binding to the Stat3 SH2 domain, suggesting that the catechol moiety is a pTyr bioisostere and may potentially be used for designing cell-permeable SH2 inhibitors.

To assess whether 9 retained affinity to PSMA compared to its Mnv control (3), a serial dilution of each compound was allowed to compete against 10 nM of IRDye800-YC27 for binding to PC-3/PIP cells.

This compound was found to compete for binding to HA with an antibody that is known to associate with the small α-helix and loop region of the stalk.

It also appeared that SB 247464 and G-CSF bound to different sites on the receptor, given that the small compound was unable to compete with G-CSF receptor natural ligand to initiate the dimerization.

Although compound B1 and C1 could not produce the pi-stacking interaction with Phe731, both compounds which possessed the lower binding energy and higher dockscore than the two control compounds were believed to compete with the ATP molecule.