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They developed a compound to block the protease, and analyzed the way the compound worked.
Johnson & Johnson has already developed a compound to block the H-3 receptor, causing the thalamus to increase its production of histamines.
Mallucci's team have found a major pathway leading to brain cell death in mice, and used an oral compound to block it.
Pfaus and his grad students inject the rodents with this or that compound to block one aspect of desire's biochemistry and isolate another.
The company originally developed the drug CVM-1118, a derivative of a plant compound, to block cancer cell growth.
In conclusion, EHop-016 has potential as an anticancer compound to block cancer progression via multiple Rac-directed mechanisms.
Similar(48)
We evaluated the capacity of these compounds to block platelet aggregation triggered by arachidonic acid.
For companies, the payoff will come later, when they develop compounds to block the newly identified drug targets.
Scientists already knew that ketamine binds to, and blocks, a receptor in the brain called NMDAR, which triggers its anesthetic effects, so Monteggia's group used other compounds to block NMDARs in mice.
To determine whether the same principle applied to our cells, HCC and PH5CH8 cells were treated with a panel of different chemical compounds to block the cell cycle.
Thus, we postulated that the ability of candidate compounds to block infection in DCs or DC-T cell co-cultures may provide a more rigorous and relevant in vitro evaluation of the capacity of potential microbicide formulations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com