Sentence examples for compound to address from inspiring English sources

In exceptional cases, the NTP may need to conduct multiple bioassays for a compound to address the carcinogenic potency for various periods of exposure (i.e., in utero only, in utero plus adult, and adult only).

Identifying how senescent cells avoid apoptosis allows for the prospective design of anti-senescence compounds to address whether homeostasis can also be restored.

Valproic acid (VPA) and methylmercury (MeHg) were used as positive control compounds to address the following fundamental questions: (1) Does transcriptome analysis allow discrimination of the two compounds?

Correlative SAR is a strategy to expand the use of existing biologically active compounds to address some of the major challenges in the postgenomic era: annotating protein functions and linking those functions to an observed phenotype.

"As tire manufacturers continue to tune their technology, we have seen improvements in the compound technology to address wear".

While these compounds were designed to address the low permeability of OT and other full length analogs, we found that reduction in molecular weight and the removal or replacement of the three amino acid tail of OT did not have a significant effect on passive permeability.

In light of these data, this report identifies emerging methodological issues in risk assessment for estrogenic compounds: the need to address differences in in vivo end points of concern and the associated mechanisms; pharmacokinetics; the crucial role of timing and duration of exposure; interactions; and non-ER-mediated activities of estrogenic compounds.

Together, the semi-preparative separation and the E-Screen bioassay act as a biomarker that will allow us not only to test individual compounds, but also to address the problems related to environmental or occupational exposure to mixtures of xenoestrogens each present at low concentrations [ 35].

To address compound identity and purity, to confirm the stock solution concentration (generally 20 mM), and to determine compound stability in DMSO under the storage conditions used, quality control analysis of the entire library is being conducted using a tiered approach.

In order to address compound mechanism of action, a lanperisone gene expression signature was derived from MEFs treated for 6 h.

In order to obtain efficacious and safe compounds, it is necessary to address the issues of potency and selectivity.