Sentence examples for compound series from inspiring English sources

Traditionally, SAR exploration has concentrated on individual compound series.

Compared to existing approaches these drawings substantially simplify the visual analysis of large compound series.

Changing substituent position revealed a more promising compound series of anti-inflammatory agents.

A long incubation time (e.g., 30 min) is more applicable to a compound series with high metabolic stability.

Additionally, data also suggest that increasing the bulk around C6 may allow control of subtype selectivity within these compound series.

Percentage of hit to lead projects that involve a specific compound or compound series whose MOA may or may not be known.

These two characteristics are usually related because high chemical tractability facilitates the generation of more compound series in vitro which, in turn, provide more optimisation options in vivo.

Selectivity against other subtypes of both protein families confirmed the pharmacological profile of the compound series, and structure activity relationships (SAR) were also deduced.

The specificity of the observed effects of the compound series was tested in cell-based assays for antiproliferation activity using Jurkat cells and PHA-stimulated PBMC.

The binding modes of these molecules add to our structural knowledge base for IspF and suggest future refinements in this compound series.

The compound series with phenyl substitution at the 2 position of the quinazoline proved to be more effective at inhibiting NF-kB function both theoretically and experimentally.