Sentence examples for compound retains from inspiring English sources
While falnidamol hydrochloride failed to transactivate VDR in HEK293T cells, induction of CYP24A1 and recruitment of RXR illustrates that this compound retains VDR functionality that may be cell dependent.
Since the aromatic domain of EerI can be replaced with a structurally distinct membrane-targeting group and the resulting compound retains almost all the activities of EerI, we assume that the major contribution of this domain is to localize EerI to the ER membrane.
As a result, this compound retains the side chain modification of CY but lacks ability to attack DNA.
This compound retains the F-amidine scaffold but is linked to a fluorescent reporter tag (rhodamine) via a p-benzylic triazole group.
Each compound retained the anti-inflammatory activity of the parent NSAID.
While 5 was negative in the Ames assay, the compound retained the ability of 1 to form certain electrophilic intermediates.
After covalent binding to a synthetic DNA duplex 16-mer, the compound retained its affinity for the ER; specificity of the binding event was demonstrated by the ability of free 17β-estradiol as a competitor to disrupt the DNA adduct-ER complex.
ZCA intercalation compound retained excellent absorption capacity in the UV region of pure CA but with slight shift in absorption peaks and broadened absorption range due to arrangement in host and host-guest interactions.
The recent advances of the LC-MS/MS device have also offered highly sensitive measurements of compound retaining in the brain following administration at a dose nearly equivalent to PET studies (approximately 2 to 10 μg/kg).
This modified compound retained the activity of efsevin to restore cardiac contractions in ncx1h deficient embryos and was used to create efsevin-conjugated agarose beads (efsevinLB).
Where the substituent was an aromatic ring directly attached to the piperidine ring (30), the compound retained reasonably potent activity (EC50=0.024 μ m); however, this compound would have decreased basicity at the piperidine ring.
