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The zebrafish offers advantages over equivalent rodent models, since the manifestation of disease phenotypes is typically more rapid than in their rodent equivalent, larvae can be arrayed in multi-well plates, and compound requirement is small.
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Early identification using cheaper, higher throughput assays with lower animal and compound requirements would be preferable.
The characteristics of fermentation are at least 3 of the following: the release of energy from a sugar or other organic compound; no requirement for molecular oxygen; no requirement for an electron transport system; or use of an organic compound as the final electron acceptor.
Work to rebuild and enlarge Euston to include new platforms for HS2 trains is expected to last more than a decade, with severe traffic disruption and pollution in the area compounding the requirement for several hundred homes to be demolished.
Development of an in vitro model for assessment of proarrhythmic potential offers the advantage of higher throughput and reduced compound quantity requirements when compared to in vivo studies.
Similar to the problem in the fabrication of planar compound eye, the requirement of precise alignment of the photodetector and microlens is hard to achieve.
Furthermore, animal studies require that the selected target or compound meets the requirements for species specificity and target specificity; thus, providing the rationale for the selection of a particular species, strain, gender and age of the animals is necessary.
The high density of the caesium formate brine (up to 2.3 g·cm−3, or 19.2 pounds per gallon), coupled with the relatively benign nature of most caesium compounds, reduces the requirement for toxic high-density suspended solids in the drilling fluid a significant technological, engineering and environmental advantage.
All DRC-1339 applications were implemented in accordance with label requirements "Compound DRC-1339 Concentrate - Feedlots"; (EPA Registration 56228-10).
Respondents further noted that the association between circumcision and illness is further compounded by the requirement to undergo HIV testing before getting circumcised.
In this case, the cell contact with hydrophobic compounds is a requirement because the first step in aromatic or aliphatic hydrocarbon degradation is the introduction of molecular oxygen into the molecules by cell-associated oxygenases [ 37].
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