Sentence examples for compound profiling from inspiring English sources

In silico screening is now incorporated in all areas of lead discovery; from target identification and library design, to hit analysis and compound profiling.

Furthermore, novel links between targets and adverse effects can be unraveled which are of interest in their own right, but which can also be applied to select targets for in vitro compound profiling.

For compound profiling, the assay was miniaturized to 4 µL in a 1536-well plate by direct volume reduction.

We further evaluated the 8 hits obtained using the Fas/FADD/Caspase-8 screen using a combination of engineered yeast cells carrying vectors designed for post-HTS compound profiling and using in vitro enzymatic assays for β-galactosidase and Caspase-8.

The NTP 1,408 compound library and compound profiling.

GC-MS with off-line extraction was mainly applied for compound profiling or semi-quantitative determination [ 31, 34, 36].

The present study is concerned with the study of bioactive compound profile of black carrot.

Structure- and knowledge-based approaches led to the design of first-in-class molecules with the desired target compound profile: dual PDE5 and HDAC6-selective inhibitors.

The optimized method was applied to three lentil genotypes with different phenolic compound profiles to provide information of value to breeding programs.

PC-1 differentiated volatile compound profiles in cultures with and without addition of yeast extract.

Due to their promiscuous nature regarding their compound profiles, and the significant overlap in substrate and inhibitor profiles of BCRP/P-gp, inter-protein similarities in ligand recognition appear quite likely, but are still elusive to researchers in the field.