The "String of Pearls" strategy formalized in 2007, threads together a library of compounds and portfolio of technologies for the purpose of accelerating the discovery, clinical development, and commercialization of new therapies across a broad range of therapeutic areas.
"But some had much, much more than that with Madoff, so their due diligence failure was compounded by poor portfolio management".
Merck plans to sail majestically on, forming a few alliances to bring outside compounds into its portfolio, but relying mainly on its own scientists to repeat successes such as Crixivan's.
Also, the effect of compounding on your portfolio is reduced in the short-term, there is the potential for increased costs, and it is very time consuming.
Assuming a conservative compounding trajectory of 6 percent for the S&P 500 Index, equity portfolio valuation compounds at a $3.5 billion annual clip.
"If you don't have big drops, the portfolio can compound at a greater rate," Mr. Goldie said.
Attempts are being made to increase productivity through process optimisation and, increasingly, through strain manipulation, which also enables a diversification in the portfolio of compounds that can be produced.
In addition, Eli Lilly and Company (Indianapolis, IN) has provided access to agents from their portfolio of compounds for screening against variola virus.
Pharmaceutical companies are facing an urgent need to increase their lead compound and clinical candidate portfolios, to satisfy market demands for continued innovation and revenue growth [ 1].
