Exact(1)
Although the mean potency of activity cliff compounds and other active compounds was overall very similar, compound pathways originating from 54% of all activity cliffs successfully reached highly potent compounds, compared to only 28% of pathways originating from compounds not involved in cliff formation.
Similar(59)
The same applies to present for protein – pathway and compound – pathway interactions, such is the case of RAC1 and "Regulation of actin cytoskeleton".
To answer this question, the computational compound pathway model schematically shown in Figure 3 was applied to monitor the progression of activity cliffs towards the most potent compounds in a data set and compare activity cliff-dependent and -independent pathways.
The metabolic reconstruction of aromatic compounds pathways in in model environmental bacteria has been achieved by genome sequence analyses [3], [12] [14].
In the 'Metabolic Engineering Target Selection' table, relationships among compounds, pathways, correlated pathways and genes are available.
The database can be browsed for compounds, pathways, reactions, enzymes, their genes and organisms.
MESSI incorporated information of compounds, pathways and genes and their relationships from KEGG database using KEGG API REST.
The tree suggested a recent evolution of the genes belonging to the alkanesulfonates and organosulfur compounds pathways.
In Clusters II and III, including ethylene and many volatile compounds, pathways enriched in positively correlated genes include the TCA and glycolysis pathways.
Although these times are arbitrary cutoffs, they allowed us to highlight some possible temporal differences in the effects of compounds' pathways.
List of proteins and their hosts used for the phylogenetic analyses of the periplasmic components from X. citri belonging to the putatives sulfate and organosulfur compounds pathways.
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