Sentence examples for compound optimization from inspiring English sources

These compounds serve as starting points for further compound optimization.

This study also demonstrates the validity of structure-guided approaches to focused library design and lead compound optimization.

Although informatics has a crucial role in addressing the challenges of modern compound optimization, it is arguably still undervalued and underutilized.

The concept of fragment-based and virtual reaction-driven design enables rapid compound optimization from scratch with a manageable complexity of the search.

In order to solve the LMI problem and to identify the chaotic systems as T S fuzzy modes, we propose a compound optimization strategy called the island-based random-walk algorithm (IRA).

infusion compared with one- or multiple time points after transient dosing, it is seldom obtained for compound optimization in early phase of CNS drug discovery due to requirement of prerequisite PK data to inform the study design.

Under ligand based lead compounds optimization, QSAR study of the bioactive compounds plays a useful role for screening of new potential lead compounds.

FBGA package reliability is usually assessed through the conventional approaches of die attach and mold compound material optimization.

Based on the molecular docking analysis compound 3g optimization work was performed, and then a new structure backbone of N-nitrourea compound was designed for further research.

Fluorination is commonly exercised in compound property optimization.

The ligand and residue side chains forming the binding pocket were treated as flexible, and their conformation was thoroughly sampled in 10 Monte Carlo (10 for compound 30) optimization steps to global convergence of the physics-based energy function.