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The system, in fact, was constituted by a recombinant phosphoenolpyruvate carboxylase (PEPC) from the thermophilic cyanobacterium Thermosynechococcus elongatus, in combination with mesophilic/thermophilic bacterial carbonic anhydrases (CAs), for converting CO2 into oxaloacetate, a compound of potential utility in industrial processes.
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Furthermore, the HTS assays were very useful for quickly identifying compounds of potential risk for further studies, thus concentrating resources on the potentially most significant chemicals.
Recently also a number of other synthetic imidazole and pyridine based compounds of potential insulin-mimetic activity have been studied in solution [16]-[17] [16]-[17]
This work demonstrates the utility of zebrafish as a screening tool for small molecules that affect eye vasculature and presents several compounds of potential therapeutic importance.
The collaborative NormaNEWS [25] joint activity has already successfully demonstrated the usefulness of the retrospective screening of high-resolution mass spectrometric data in establishing the spatial and temporal occurrences of newly identified compounds of potential emerging concern [26].
According to our results, the design of molecules with the side chain bound to the ethylene part of the triphenyl ethylene skeleton might generate compounds of potential pharmacological interest.
Future work will involve screening of larger and more relevant chemical compound libraries with a view to identifying lead compounds of potential clinical significance.
These propargylic alcohols were used to construct multicyclic organic compounds of potential biological and pharmaceutical applications.
In recent years, agricultural scientists have begun to explore novel strategies for isolating plant compounds of potential medicinal value.
Further work is needed to evaluate the role of gain-of-function β-catenin with respect to additional anticancer compounds of potential use in treatment of colorectal cancer.
This, and the fact that the entire universe of compounds of potential toxicologic interest stretches into the tens of thousands, means that many important compounds were not included in this initial set of 1,353.
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