Sentence examples for compound mechanisms from inspiring English sources
It has been shown previously that 3D cultures can be more or less sensitive than 2D cultures to compound effects and that these relative sensitivities correlate with compound mechanisms of action.
As functional screens are being performed on increasingly large numbers of compounds or genetic perturbations, often with poorly characterized mechanisms or strong off-target effects, jointly modeling each compound in the context of the full screening collection should yield novel insights into compound mechanisms.
This presented compound mechanism may well improve the procurement efficiency of divisible goods and greatly reduce the procurement risk.
Pools of strains grown competitively in the presence of bioactive compounds generate characteristic profiles of strain sensitivities reflecting compound mechanism of action.
Moreover, the implementation, availability, and feasibility of the two-stage compound mechanism are highlighted by using an example of the multi-source procurement of electricity coal.
By considering both the risk attributes and the attributes under a commercial criterion, we design a new two-stage compound mechanism for supplier selection based on multi-attribute auction and supply chain risk management.
Gene expression profiling of cellular perturbations has been used to effectively predict drug sensitivity (Chambers et al., 1999; Ayers et al., 2004) and compound mechanism-of-action (MoA) (Iorio et al., 2010), as well as for anti-cancer drug discovery (Stegmaier et al., 2004; Lamb et al., 2006; Li et al., 2012b; Lee et al., 2016).
Some regulators are finding that these data have the potential to add to the body of knowledge about compound mechanism of action.
In order to address compound mechanism of action, a lanperisone gene expression signature was derived from MEFs treated for 6 h.
We fully anticipate that subsequent studies will elucidate these compounds' mechanisms of action, leading us to a fuller understanding of the pathways that regulate Treg cell differentiation.
FDA approved ascidian compounds mechanism of action along with other compounds status of clinical trials (phase 1 to phase 3) are discussed here in.
