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The stereochemistry of the title compound is established as meso.
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Furthermore, the potency, affinity and mechanism of action of a new non ATP-competitive compound were established.
Target specificity of the lead compound was established by demonstrating direct binding of the compound to Magmas and by genetic studies.
Factors of fine control over ternary systems wherein DNA and a synthetic polyanion compete for binding with the cationic compound were established.
Mahandrihono, the largest compound, was established between 1710 and 1730 by King Andriambelomasina; it remains largely intact and contains the royal tombs, house of King Andrianampoinimerina, summer palace of Queen Ranavalona II, and sites that figured in key royal rituals such as the sacrificial zebu pen, royal bath and main courtyard.
The purity of active compound was established by TLC and HPLC.
The structure of the active compound was established with the use of spectroscopic methods.
The molecular formula of this compound was established based on the mass spectrum MS (m/z) [M-H]: 235.12.
Dioscorealide B was re-crystallized from methanol and identity of this compound was established by using H and C NMR in Table 1.
The structure of the active compound was established with the use of spectroscopic methods (EI-MS, H NMR, C NMR, H-H COSY, HMBC, HMQC, and DEPT).
The structure of this compound was established on the basis of EI-MS data together with H and C NMR spectra as shown in Figure 2(a).
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