Sentence examples for compound interactions from inspiring English sources
Our study highlights the sensitivity of DFS experiments to dissect protein-metal compound interactions.
Compound descriptor array based methods use machine learning approaches to relate compound interactions with arrays of observations regarding a compound.
The first of these would be non-target compound interactions not directly involved in the therapeutic mechanism of action, such as albumin binding or metabolic turnover by P450s.
Overall, induction of cell death by dependent and independent-DNA-metal compound interactions were possible using imidoyl-indazole Pt II) complexes as anticancer agents.
As a consequence, the in vitro measured K d alone provides not sufficient information to characterize complex compound interactions and the potential in vivo effectiveness of small-molecule drugs, but rather the in vitro assessment of radioligand-receptor binding kinetics.
Recent studies confirmed the necessity of studying multiple distinctionic ion channels which are responsible for cardiac related diseases or TdP, to obtain an improved clinical TdP risk prediction of compound interactions and also for designing drugs.
Using broad-range and specific probes, and by overexpression of various SHs in planta, we are able to confirm eight SH-compound interactions, including selective inhibition of carboxylesterase CXE12, prolyloligopeptidase, methylesterase MES2 and tripeptidyl peptidase TPP2.
A distinction can be made between protein-protein interactions (PPI), domain-domain interactions (DDI), metabolic pathways, signaling pathways, transcription factors, gene regulatory networks and protein-compound interactions.
We plan to add new data including host-pathogen interactions, specific gene and protein expression patterns, relationships between potential targets and chemical compounds and/or moieties, protein-compound interactions and single nucleotide polymorphisms (SNPs).
These protein-compound interactions provide the opportunities to explore the molecular binding mechanisms.
Consequently, the protein-compound interactions are clustered by two-way hierarchical clustering.
