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The potential the compound has to save healthy brain tissue and improve patients' lives is told in a short film called Bringing Light, which is in the running for the Sundance Film Festival.
Before a redox-active compound can be used as a new internal reference for reporting electrode potentials in ionic liquids, its suitability as a reference compound has to be proven.
An increasing number of clinical trials are being performed to assess the absence of relevant differences between two treatments, in which the efficacy of a new compound has to be proven through demonstrating noninferiority as compared with a standard treatment.
For instance, NiOOH compound has to be originated on the surface to initiate the electrochemical activity.
When selecting relevant hypotheses the query compound has to be in the applicability domain of the retained hypotheses.
For instance, in case of the nickel, NiOOH compound has to be synthesized on the surface to initiate the electrochemical activity [46].
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The pIC50 value of a compound had to be at least 5.00.
The minimum base peak intensity of the MS/MS spectrum of the native compound had to exceed 100 counts.
Thus, smaller sets of compounds have to be synthesized and tested, lab resources are saved.
Selected identified compounds have to be fully confirmed by means of analytical standards as reference.
It is therefore clear that in the case of F508del and other trafficking mutations, novel compounds have to be identified.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com