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This compound effect was therefore investigated through the examination of the kinetic data of all of the three processes, and quantified in terms of the UV intensity and dosages of the reagent used.
A number of PI3Kγ kinase inhibitors have been shown to block T-cell functions but interpretation of PI3Kγ biology from compound effects is limited by the target selectivity of compounds 13.
The compounded effect is, you can never quite settle into this virtual retreat. .
Compound effects were assessed by direct inspection of animals in microtiter plate wells using a stereomicroscope or of images captured by a CCD camera.
Compound effects were evaluated using the parameter calcein AM-positive cells per spheroid, and results are shown in Supplementary Table S3.
These results suggest that a full range of similarities and differences in compound effects are potentially detectable using cell-based qHTS.
The similarity score of the compounds' effects is dependent on the sequence of treatment with the two compounds, which agrees with the widely observed phenomena that the sequence of drug treatment matters to patients' outcomes.
Compounds effects were compared to vehicle; ***p < 0.001; n.s.s
BSO is known to be a relatively nontoxic compound whose effect is apparently restricted to the inhibition of γ-glutamylcysteine synthetase [53].
When it hovers between 5 and 7, as it does in some 20 countries, the "compounded interest" effect is extremely powerful.
The most important compounds, whose effect is based on DNA interaction, are anthracyclines, cytotoxic antibiotics, and platinum-based cytostatics [ 18– 218.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com