But instead, we go the other way -- compounding our dysfunction, and encumbering our interactions with culture with only the follies of our genomic forays.
The impairment of one sensory channel may be further compounded by dysfunction in another, as it happens, for example, in the visual and vestibular systems.
Compounding this dysfunction is the observation that inflammatory cytokines (e.g., IFNγ, TNFα) serve to enhance the activity of both γ-secretase [ 90] and β-secretase, increasing the production of Aβ and the formation of senile plaques [ 163], and eventually creating a self-perpetuating cycle of inflammation and Aβ deposition.
Additive approaches based on grouping substances by effects (e.g. summing up doses of compounds causing dysfunction of the nervous system in humans but acting via differing mechanisms) requires testing results obtained under comparable conditions and evaluating effects on a common human health endpoint.
The present study was designed to investigate the pre-treatment effects of naringenin (NAR), a polyphenolic compound on cognitive dysfunction, oxidative stress in the hippocampus, and hippocampal neuron injury in a rat model of AD-TNDCI.
The lack of objective data on exposure, and the inability of routine physical examinations and tests to detect subtle neurological dysfunction compound the inability to find answers to this problem.
Application of these methods to assess both androgenic, estrogenic, and anti-steroidogenic properties of environmental contaminants in a single fish species will be a valuable tool for identifying compounds causing reproductive dysfunction in fishes.
Myocardial edema due to excess fluid administration compounds the myocardial dysfunction common in critically ill patients [21].
A woman's perception of losing sexual attractiveness is compounded when sexual dysfunction becomes a reality following surgery.
Myocardial edema due to excess fluid administration compounds the myocardial dysfunction common in critically ill patients [ 21].
