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We chose not to consider "character-based" approaches (e.g. [ 28]) because nucleotide synapomorphies are unlikely to be pure (i.e. consistency index = 1 [ 10]) and compound diagnostics have proven unwieldy [ 29- 31].
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All the four species of Gossypium were identified by simple or compound diagnostic characters using ITS.
Indeed, genetically engineered yeast expressing an olfactory receptor and its signal transduction system have been shown to be capable of detecting 2,4-dinitrotoluene, a compound diagnostic of explosives [31].
The specific testing infrastructure of vertical disease programs can further compound diagnostic delays.
Because compound diagnostic characters are a valuable source of information to diagnose species [ 18] we filtered variable characters for each sister-species pairs in PAUP 4.10b [ 41], and fixed substitutions were selected in MacClade 4 [ 40].
Compound diagnostic characters are a valuable source of information to diagnose species [ 18, 44], so we filtered all the variable characters for each gene partition in PAUP*, and the selected the fixed substitutional differences between each highly supported clade within water rails.
Without them, important resources, medicinal compounds, diagnostic wisdom and ecological process would be unknown to all of science.
were embedded and frozen in Tissue-Tek® optimal cutting temperature compound (Somagen Diagnostics, Edmonton, Alberta, Canada), sectioned at 5- μm thickness using a CM1850 UV cryostat (Leica, Wetzlar, Germany), and mounted on Fisherbrand Plus microscope slides.
However the difficulties in detecting early lesions with confidence [ 11] combined with the possible interrater variations of histopathological evaluations [ 12] compound the diagnostic challenges.
Somatic cell nuclear reprogramming is opening new doors for the modeling of human disease phenotypes in vitro, the identification of novel therapeutic compounds and diagnostic factors as well as future autologous cell replacement therapies.
This article reviews the evolution of 99mTc dating back to its discovery, the development of 99Mo/99mTc generators, and the efforts to exploit the diverse chemistry of the element to explore a spectrum of compounds for diagnostic imaging, planar, and single photon emission computed tomography.
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