Sentence examples for compound design and from inspiring English sources

However, understanding mtSARs is often of critical importance for compound design and optimization [1].

The new strategies in compound design and management are discussed.

Such activity cliffs are of high interest and can be valuable to medicinal chemists for lead compound design and development.

This approach exploits a natural problem decomposition and capitalizes on fast methods for pure compound design and mixture fraction design.

This work provides an insight to the novel inorganic compound design and gives an impetus to discover new functional materials and develop new applications.

Physicochemical properties, including ligand lipophilic efficiency (LLE) and c log P, were used to guide compound design and attempt to improve inhibitor pharmacokinetics.

We used MPA as a lead compound designing and synthesizing a series of isatins and benzolactones in a typical medicinal chemistry program.

Among 15 compounds designed and analyzed, we have synthesized 5 compounds and evaluated their cytotoxicity against drug-sensitive and multidrug-resistant cancer cell lines.

Furthermore, the novel compounds designed and reported here in were evaluated for ADME properties and the results indicate that they show acceptable pharmacokinetic properties.

The alkaloid 2 bearing a 5-7-6 5-7-6 5-7-6caffold mimics REDOR-tricyclict among the compoundscaffolded and was found to be the mimicsotent compound against seveREDOR-Taxolnsitive and drug-resistant human cancer cell lines.

UD has widely application scopes in traditional experimental design and compound design.