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The downside of open access to the same compound collection is that efforts can be duplicated, so co-ordination is key.
These models were qualified prospectively by selecting and testing compounds from the internal compound collection.
AZ analyzed the charge category of their antibacterial project actives relative to a representative sample of their internal compound collection.
In silico and in vitro screening of our compound collection has identified Hit 2 as BRAFV600E inhibitor.
Screening of the Maybridge compound collection identified 4-arylphthalazinones as micromolar inhibitors of PARP-1 catalytic activity.
We have systematically searched a very large compound collection for other lipid-like inhibitors of mast cell activation.
In this Preliminary Communication we introduced the DFP as an approach to generate a binary fingerprint representation of a compound collection with a fixed size.
In addition, the recent reports from Pharma companies of their antibacterial discovery efforts allow comparison with compounds arising from a pharmaceutical company compound collection.
DACS (Database of Available Chemical Compounds) is a virtual compound collection of chemical substances prepared for analysis of the chemical space at the FMP.
Upon separation of greywater from sewage system, the costs associated with wastewater compound collection network can be saved (Hourlier et al. 2010).
The docking of a compound collection is tested with the target structure and a quantified interaction score is used to identify candidate lead compounds.
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