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The calculations were performed on the truncated active site model compound bound to quinoline.
A crystal structure of one rigid compound bound to BRAF confirmed its binding mode.
The X-ray crystal structure of the 5-formyl compound bound to cdk2 has been determined to 2.3 Å resolution.
This compound bound to human P2X7 receptors expressed in HEK transfected cells with KD and Bmax value of 3.46 ± 0.1 nM and 727 ± 73 fmol/mg of protein, respectively.
The compound bound to DNA as effectively as cisplatin, but did not block RNA polymerase II-mediated transcription as strongly as cisplatin, indicating that once the compound formed Pt-DNA lesions, the salicylanilide group was more easily recognized and removed.
We computed the van der Waals energy of each complex consisting of compound bound to the SH2 domain of Stat1 or Stat3 using Lennard-Jones potential with ECEPP/3 force field [30].
Similar(46)
This chapter discusses that isothermal titration calorimetry (ITC) follows the heat change when a test compound binds to a target protein.
This compound binds to chitin present in the yeast cell wall.
This compound binds to native Epac and the Epac H30 sensor, but not to the PKA-RIβ.
This compound binds to the enzyme in close proximity to the catalytic center.
This compound binds to estrogen receptor in mammal cells, downregulating its activity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com