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OTA is also a carcinogenic, teratogenic and immunotoxic compound, affecting both humoral and cell-mediated immunity [15].
The successful implementation of a high-throughput chemical genetic screen and the identification of a small-molecule compound affecting plant immunity indicate that chemical genetics is a powerful tool to study whole-organism plant defense pathways.
According with the compound affecting NOS, the reduction in LTP caused by 1400W could be prevented by co-application of an NO donor.
As an example, we use the present model to simulate furosemide injections and our results are compatible with experimental data demonstrating that our model would be appropriate to test the action of other pharmacological compound affecting the homeostasis in the future.
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However, it has also been suggested that this compound affects the vascular system.
The first part examines the question: how will employing multiple conformers per compound affect the 3-D similarity score between two randomly selected biologically-tested compounds?
Drug therapy is often directed to specific organ and tissue compartments where the mode of action of the compound affects specifically targeted biological processes.
Although each compound affected a distinctive expression pattern, a common group of genes and pathways were significantly affected by most of the compounds.
Neither compound affected the fluorescence of NATA.
The torsion of compounds could help us understand the interaction site while the compound affects protein.
Neither compound affected the CXCL10 signal assay or produced an AC50 in the TIE2 assay.
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