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We presented a method to calculate five risk factors: the above four factors plus a composite risk factor.
Therefore, this prospective analysis of data from older, Japanese-American men demonstrated that decreased LDL size is a univariate predictor of incident CHD, and that a composite risk factor of LDL size, triglyceride, and HDL cholesterol was a risk factor for CHD independent of other risk factors.
The composite risk factor score was used in order to compensate for the day-to-day fluctuation in the single risk factors and included the same variables as in previous studies by our group.
However, these differences were more subtle than might have been expected, considering the differences among the cohorts of each composite risk factor used in the CVD risk score calculation.
Since there is no clear definition and the prevalence rate is relatively low, several authors have derived a continuous score representing a composite risk factor index (i.e., the metabolic syndrome score).
However, despite the differences in age, race/ethnicity, and reproductive risk factors, the groups did not significantly differ on percentages of women at high risk for developing breast cancer based on the Gail composite risk factor score.
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In exploratory analyses stratified by SE dose (0, 1 or 2 copies) rather than SE positivity, there were marked differences in the associations of composite risk factors of GSTM1 status and SE dose with ACPA positivity.
Age- and gender-adjusted associations of composite risk factors with ACPA positivity are summarized in Table 3. aACPA, anticitrullinated protein antibody; CI, confidence interval; GSTM1, glutathione S-transferase Mu-1; OR, odds ratio; SE, shared epitope; SONORA, Study of New-Onset Rheumatoid Arthritis; VARA, Veterans Affairs Rheumatoid Arthritis Registry.
We aimed to increase aerobic fitness, physical activity, and quality of life while decreasing body fat and a composite cardiovascular risk factor score in the intervention group compared with the control group.
Since there is no universal definition of the metabolic syndrome in children or adolescence and the prevalence rate is relatively low, several authors [ 19- 28] have derived a continuous score representing a composite CVD risk factor profile or index (i.e., the metabolic syndrome score).
The four risk factors with the highest AUC for death within 5 years that appeared to be independent from each other were used to generate a composite risk score where each factor added 1 point.
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