Assignment to each group for the corresponding defect was performed randomly, and each group was composed of six animals (six defects for each group).
Motor coordination, measured as latency to fall by weekly performed rotarod test, showed steady downhill in both Ndufs4 −/− ::Opa1 tg and Ndufs4 −/− groups, each composed of six animals.
Each group was composed of four animals; one technical repeat was done for a non-treated male and a doxorubicin-treated male.
Each group was further divided into seven subgroups composed of eight animals per subgroup: 1) untreated group, 2) NSS-treated group, 3) Tween 20®-treated (vehicle control) group, 4) HexE-treated group, 5) EtAcE-treated group, 6) MeE-treated group, and 7) AqE-treated group.
The system was composed of three main parts, including one small animal stereotactic frame, one imaging-fusion software and an automatic robot arm system.
Participants learned events composed of three or four elements (locations, people, and objects or animals) during a study phase.
Human mitochondrial RNase P, the first to be identified and possibly the prototype of all animal mitochondrial RNases P, is composed of three proteins.
All members of PAPs contain a characteristic set of seven amino-acid residues involved in metal ligation and a binuclear metallic center composed of two irons in animals, whereas one iron ion is replaced by either a zinc or manganese ion in plants [22].
The authorization process implies the hearing of the application and ethical judgement by an independent animal protection board which is composed of six persons from animal protection organisations and scientific community.
University education is composed of three levels.
