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Randomization of individuals is not always feasible and interventions are usually composed of multiple factors.
Researchers have conceptualised local environments as composed of multiple factors influencing the macro-level (legislation and policy), the physical environment level (access and availability of foods at home, work, shops etc).
However, a study conducted in Australia using a neighborhood-level SES index composed of multiple factors such as income and unemployment demonstrated no modification of the association between O3 exposure during days 31 60 of gestation and abdominal circumference during gestation despite some evidence of an inverse association in the highest SES quartile (Hansen et al. 2008).
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Therefore, these matrices were composed of multiple component communities [25].
Each classifier composed of multiple gene features became a gene set.
Within a condition, each TF network contributed one classifier composed of multiple gene features.
Biomarker signatures, composed of multiple circulating factors, may also have potential value as predictive biomarkers.
This strategy identified both mucus production and secretion related genes under control of a network composed of multiple transcription factors.
Taken together, biofilm formation in Salmonella is controlled by a regulatory network composed of multiple transcriptional factors, secondary messengers, and sRNAs.
The latter parameter is, however, difficult to measure as it is composed of multiple hemodynamic factors such as central venous pressure, coronary venous pressure, extravascular compressive forces such as LV end-diastolic pressure, and is further complicated by zero flow pressure [ 3].
While the relationship between the number of individuals carrying a certain genetic risk factor and the risk of disease in the population was shown to influence the screening performance for a single marker [ 15], we have proven this is also true for a genetic test composed of multiple genetic risk factors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com