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To gain more insight into the relationship between misfolded SOD1 and individual components of the molecular motor protein complex, we compared sedimentation of misfolded SOD1 in linear density gradient centrifugation with that of representative molecules that compose motor complexes in motor axon lysate.
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The mNSS used here was composed of motor and balance tests; the reflex test was eliminated due to habituation of the mice after repeat testing.
The peripheral nervous system is composed of motor and sensory neurons with their cell bodies in the spinal cord and long cytoplasmic extensions called axons, which signal with a distant target organ.
The loss of fast fatigable motor units composed of large motor neurons innervating type IIb fast glycolytic fibers before any apparent motor symptoms (Frey et al, 2000; Hegedus et al, 2008) suggests that the metabolic signature of glycolytic fibers may predispose them to NMJ dismantlement, one of the first pathologic events in the course of the disease (Fischer et al, 2004).
Although there is a broad taxonomic distribution of the CobN gene among cobalamin-dependent organisms, a much narrower distribution is observed for the genes that compose the AAA+ motor complex (CobS and CobT) (Rodionov et al. 2003).
Different schematics of hysteresis, reluctance "trapped field" and composed HTS motors are discussed.
Motor proteins are generally composed of a motor head domain that converts chemical energy to force, and a range of additional domains that bind cargo, filaments or accessory proteins (e.g. [ 18, 19]).
The motor is based on an electrostatic film motor composed of two thin plastic films containing fine pitch three-phase electrodes, which face each other across a short gap.
The XYZ stage controller is composed of a motor controller (g) for controlling the stepping motors (i) of the XYZ stage, and an ADC (f) for digitizing the signal of the SQUID output.
Open image in new window Fig. 1 Mechanical transmission model composed of traction motor, gearbox, wheelset axle, wheels and brake system.
The first subsystem is the electromechanical system composed by a motor, cart and pendulum, and the second is an elastic barrier.
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